Muleshoe National Wildlife Refuge is the oldest National Wildlife Refuge in the state of Texas, having been established in 1935. It is located about twenty miles south of Muleshoe, the seat of Bailey County. It is some fifteen miles north of Morton on Texas State Highway 214.
The 5,000-acre refuge is a stop for migratory waterfowl flying between Canada and Mexico. If sufficient water is present, during the winter it hosts tens of thousands of sandhill cranes. The largest number of cranes ever recorded was 250,000, during February, 1981.